Tumor Type

Australia
Canada
(partner)
Pancreatic Cancer - Ductal adenocarcinoma
Australian Pancreatic Cancer Genome Initiative  HTML ; 
Funding Organizations
Australia: National Health and Medical Research Council
Australia: Queensland State Government
Australia: University of Queensland
Australia: Institute for Molecular Bioscience
Australia: Cancer Council New South Wales
Australia: Garvan Institute of Medical Research
Research Organizations
Australia: Australian Pancreatic Cancer Genome Initiative
Australia: Queensland Centre for Medical Genomics
Italy: University of Verona
United States: Johns Hopkins University
United States: University of California, San Francisco
Australia: Institute for Molecular Bioscience
Australia: Garvan Institute of Medical Research
Research Activities
Publication Policy
1:   QCMG Project Specific Moratorium HTML 
2:   ICGC Goals, Structure, Policies and Guidelines Section E.3 - Publication Policy HTML 
3:   Template Letters to Facilitate Communications HTML 
to ensure appropriate dialogue between data users and generators and for authors to contact ICGC members and editors
Clinic & Pathology
Australia: Australian Pancreatic Cancer Genome Initiative
Garvan Institute of Medical Research
Italy: University of Verona
United States: Johns Hopkins University
University of California, San Francisco
Sequencing & Analysis
Australia: Institute for Molecular Bioscience
Complementary Studies
Australia: Garvan Institute of Medical Research
Institute for Molecular Bioscience
Data Storage, Analysis & Management
Australia: Garvan Institute of Medical Research
Institute for Molecular Bioscience
Project Summary

The primary aims of the Australian Pancreatic Cancer Genome Initiative (APGI) are to deeply sequence tumor and normal gDNA, survey global gene expression (by RNAseq approaches), and determine genome wide patterns of methylation of ~375 pancreatic cancer patients.

The goal is to use the best clinical material available, with well-characterised and accurately annotated clinico-pathological, treatment and outcome data acquired prospectively.

Principal Investigators

Institute for Molecular Bioscience
• Sean M. Grimmond (overall lead)
• David Miller
• Conrad Leonard
• Nicola Waddell
• Peter Wilson
• John V. Pearson
• Karin Kassahn

Garvan Institute of Medical Research
• Andrew V. Biankin (pancreatic cancer lead)
• Robert L. Sutherland
• James G. Kench
• Susan M. Henshall
• Liz A. Musgrove
• Roger J. Daly

Johns Hopkins University
• Ralph H. Hruban
• James R. Eshleman
• Anirban Maitra
• Christine Iacobuzio-Donahue

University of California, San Francisco
• Margaret A. Tempero

University of Verona
• Aldo Scarpa
• Paolo Pederzoli
• Claudio Bassi
• Rita Lawlor

Lead Jurisdiction