Overview

ICGC Goal: To obtain a comprehensive description of genomic, transcriptomic and epigenomic changes in 50 different tumor types and/or subtypes which are of clinical and societal importance across the globe.

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Announcements

  • 15/March/2012 - The ICGC Data Coordination Center (DCC) is pleased to announce the release of Version 8 of the ICGC data portal.

    This update includes first data releases from France’s Liver Cancer project, Germany’s Pediatric Brain Cancer project, and the United Kingdom’s Myelodysplastic Syndrome Project. Also included are new submissions from the Australian Pancreatic Cancer project, the Canadian Pancreatic Cancer project, the Japanese Liver Cancer project, and the United Kingdom Breast Cancer (Triple Negative) project.

    This data adds to previous data releases from the Chinese Gastric Cancer project, the Spanish Chronic Lymphocytic Leukemia project and submissions from The Cancer Genome Atlas in the United States, which has contributed information on about 10 types of cancer affecting the blood, brain, breast, colon, kidney, lung, ovaries, rectum, stomach and uterus.

    In total, 600 newly-available cancer datasets are provided in this release, with the ICGC data portal now containing data from 3,561 cancer genomes.

Updates

  • Currently, the ICGC has received commitments from funding organizations in Asia, Australia, Europe and North America for 47 project teams in 15 jurisdictions to study over 21,000 tumor genomes. Projects that are currently funded are examining tumors affecting the bladder, blood, bone, brain, breast, cervix, colon, head and neck, kidney, liver, lung, oral cavity, ovary, pancreas, prostate, rectum, skin, soft tissues, stomach, thyroid and uterus. Over time, additional nations and organizations are anticipated to join the ICGC. The genomic analyses of tumors conducted by ICGC members in Australia and Canada (pancreatic cancer), China (gastric cancer), France (liver cancer), Germany (brain cancer), Japan (liver cancer), Spain (blood cancer), the UK (blood, breast, lung and skin cancer) and the USA (blood, brain, breast, colon, kidney, lung, ovarian, rectal, stomach and uterine cancer) are now available through the Data Coordination Center housed on the ICGC website at www.icgc.org.
  • Cover of Nature 464 International network of cancer genome projects. Nature 464, 993-998 (15 April 2010)

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About ICGC

The International Cancer Genome Consortium (ICGC) has been organized to launch and coordinate a large number of research projects that have the common aim of elucidating comprehensively the genomic changes present in many forms of cancers that contribute to the burden of disease in people throughout the world.

The primary goals of the ICGC are to generate comprehensive catalogues of genomic abnormalities (somatic mutations, abnormal expression of genes, epigenetic modifications) in tumors from 50 different cancer types and/or subtypes which are of clinical and societal importance across the globe and make the data available to the entire research community as rapidly as possible, and with minimal restrictions, to accelerate research into the causes and control of cancer. The ICGC facilitates communication among the members and provides a forum for coordination with the objective of maximizing efficiency among the scientists working to understand, treat, and prevent these diseases.

ICGC Cancer Genome Projects

Committed projects to date: 47

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